• > 50%, or nadir ≥ 20% x 109 /L
  • 30 - 50% fall, or nadir 10 - 19 x 109 /L
  • < 30% fall, or < 10 x 109 /L
  • Days 5 to 10, or ≤ day 1 with recent heparin (past 30 days)
  • > Day 10 or timing unclear, or < day 1 if heparin exposure within past 30 - 100 days
  • < day 4 (no recent heparin)
  • Proven thrombosis, skin necrosis, or acute systemic reaction after heparin bolus
  • Progressive recurrent, or silent thrombosis, erythematous skin lesions
  • None
  • None evident
  • Possible
  • Definitive
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